Version 5.4
Homo sapiens Gene: MAP1A
Summary
InnateDB Gene IDBG-8589.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAP1A
Gene Name microtubule-associated protein 1A
Synonyms MAP1L; MTAP1A
Species Homo sapiens
Ensembl Gene ENSG00000166963
Encoded Proteins
IDBP-8591
microtubule-associated protein 1A
IDBP-8593
microtubule-associated protein 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:43510958-43531620
Strand Forward strand
Band q15.3
Transcripts
ENST00000382031 ENSP00000371462
ENST00000300231 ENSP00000300231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0016787 hydrolase activity
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007605 sensory perception of sound
GO:0008152 metabolic process
Cellular Component
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027254
View Gene Order
ENSBTAG00000014001
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.194301 Hs.619338
RefSeq NM_002373 XM_005254385
HUGO
OMIM
CCDS CCDS42031
HPRD 02549
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca