Version 5.4
Homo sapiens Gene: RER1
Summary
InnateDB Gene IDBG-86207.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RER1
Gene Name RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157916
Encoded Proteins
IDBP-86209
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
IDBP-86211
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
IDBP-86215
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
IDBP-86217
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
IDBP-363020
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
IDBP-722611
IDBP-808442
retention in endoplasmic reticulum sorting receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:2391775-2405444
Strand Forward strand
Band p36.32
Transcripts
ENST00000378518 ENSP00000367779
ENST00000306256 ENSP00000302088
ENST00000378513 ENSP00000367774
ENST00000378512 ENSP00000367773
ENST00000443438 ENSP00000417000
ENST00000493207
ENST00000488353 ENSP00000464222
ENST00000462129
ENST00000605895 ENSP00000475168
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0033130 acetylcholine receptor binding
Biological Process
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0007528 neuromuscular junction development
GO:0071340 skeletal muscle acetylcholine-gated channel clustering
GO:0090004 positive regulation of establishment of protein localization to plasma membrane
Cellular Component
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029048
View Gene Order
ENSBTAG00000009307
Not yet available
Cross-References
SwissProt
TrEMBL Q5T093
UniProt Splice Variant
Entrez Gene 11079
UniGene Hs.741204
RefSeq NM_007033 XM_005244713 XM_006710306 XM_006710307
HUGO HGNC:30309
OMIM
CCDS CCDS41232
HPRD 17967
IMGT
EMBL AL513477
GenPept
RNA Seq Atlas 11079

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca