Version 5.4
Homo sapiens Gene: TPD52L2
Summary
InnateDB Gene IDBG-87345.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPD52L2
Gene Name tumor protein D52-like 2
Synonyms D54; TPD54
Species Homo sapiens
Ensembl Gene ENSG00000101150
Encoded Proteins
IDBP-87347
tumor protein D52-like 2
IDBP-87349
tumor protein D52-like 2
IDBP-87351
tumor protein D52-like 2
IDBP-87353
tumor protein D52-like 2
IDBP-87355
tumor protein D52-like 2
IDBP-87357
tumor protein D52-like 2
IDBP-87359
tumor protein D52-like 2
IDBP-806654
tumor protein D52-like 2
IDBP-806655
tumor protein D52-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:63865228-63891545
Strand Forward strand
Band q13.33
Transcripts
ENST00000369927 ENSP00000358943
ENST00000217121 ENSP00000217121
ENST00000352482 ENSP00000344647
ENST00000351424 ENSP00000340006
ENST00000346249 ENSP00000343547
ENST00000358548 ENSP00000351350
ENST00000348257 ENSP00000343554
ENST00000474176
ENST00000615907 ENSP00000482024
ENST00000611972 ENSP00000482370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
Experimentally validated
Total 52 [view]
Protein-Protein 51 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0044822 poly(A) RNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000827
View Gene Order
ENSBTAG00000021232
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001243891 NM_001243892 NM_001243894 NM_001243895 NM_003288 NM_199359 NM_199360 NM_199361 NM_199362 NM_199363
HUGO
OMIM
CCDS CCDS13540 CCDS13541 CCDS13542 CCDS13543 CCDS13544 CCDS13545 CCDS58785 CCDS74752 CCDS74753
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca