Version 5.4
Homo sapiens Gene: GOLGA2
Summary
InnateDB Gene IDBG-87806.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLGA2
Gene Name golgin A2
Synonyms GM130
Species Homo sapiens
Ensembl Gene ENSG00000167110
Encoded Proteins
IDBP-381476
golgin A2
IDBP-381477
golgin A2
IDBP-381478
golgin A2
IDBP-810635
golgin A2
IDBP-810625
golgin A2
IDBP-810637
golgin A2
IDBP-810641
golgin A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:128255829-128275995
Strand Reverse strand
Band q34.11
Transcripts
ENST00000421699 ENSP00000416097
ENST00000450617 ENSP00000409271
ENST00000458730 ENSP00000411598
ENST00000462089
ENST00000496221
ENST00000486411
ENST00000461031
ENST00000470630
ENST00000490257
ENST00000468488
ENST00000490628 ENSP00000473603
ENST00000609374 ENSP00000476265
ENST00000611957 ENSP00000478799
ENST00000610329 ENSP00000481685
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 92 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 92 [view]
Protein-Protein 91 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007021 tubulin complex assembly
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005874 microtubule
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002546
View Gene Order
ENSBTAG00000011317
Not yet available
Pathways
NETPATH
REACTOME
REACT_1100
Golgi Cisternae Pericentriolar Stack Reorganization pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt
TrEMBL B7ZC06
UniProt Splice Variant
Entrez Gene 2801
UniGene Hs.155827 Hs.680092
RefSeq NM_004486 XM_005251930
HUGO HGNC:4425
OMIM 602580
CCDS CCDS6896
HPRD 03989
IMGT
EMBL AL590708
GenPept
RNA Seq Atlas 2801

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca