Version 5.4
| Homo sapiens Gene: SPANXC | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-88143.5 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | SPANXC | ||||
| Gene Name | SPANX family, member C | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Gene | ENSG00000198573 | ||||
| Encoded Proteins |
SPANX family, member C
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that contains a consensus nuclear localization signal but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. [provided by RefSeq, Jul 2008] Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome X:141241463-141242496 | ||||
| Strand | Reverse strand | ||||
| Band | q27.2 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
| No orthologs found for this gene | |||||
| Cross-References | |||||
| SwissProt | Q8TAD1 Q9NY87 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 64663 | ||||
| UniGene | |||||
| RefSeq | NM_022661 | ||||
| HUGO | HGNC:14331 | ||||
| OMIM | 300330 300671 | ||||
| CCDS | CCDS14673 | ||||
| HPRD | 02270 | ||||
| IMGT | |||||
| EMBL | AJ238277 AJ457790 AJ457792 AJ457795 AL109799 AY787084 AY787086 AY787088 AY787089 AY787091 AY787093 AY787095 AY787096 AY787097 AY787098 AY787099 AY787100 AY787102 AY787103 AY787104 AY787105 AY787106 AY787107 AY787108 AY787109 AY787110 AY787111 AY787112 AY787113 AY787114 AY787116 AY787117 AY787119 AY787121 AY787122 AY787124 BC005382 BC054023 BC062672 DQ994211 DQ994213 DQ994214 DQ994215 DQ994216 DQ994217 DQ994218 DQ994219 DQ994220 DQ994222 DQ994223 DQ994225 DQ994227 DQ994228 DQ994229 DQ994230 DQ994231 DQ994232 DQ994233 DQ994234 DQ994235 DQ994238 DQ994239 EF101635 EF101636 EF101638 EF101639 EF101640 EF101641 EF101642 EF101643 EF101644 EF101645 EF101646 EF101647 EF101648 EF101649 EF101651 EF101652 EF101653 EF101654 EF101655 EF101656 EF101657 EF101658 EF101659 | ||||
| GenPept | AAH05382 AAH54023 AAH62672 AAW47309 AAW47310 AAW47312 AAW47313 AAW47314 AAW47315 AAW47317 AAW47318 AAW47319 AAW47320 AAW47321 AAW47322 AAW47324 AAW47325 AAW47326 AAW47327 AAW47328 AAW47329 AAW47330 AAW47331 AAW47332 AAW47333 AAW47334 AAW47335 AAW47336 AAW47338 AAW47339 AAW47341 AAW47343 AAW47344 AAW47346 ABK19852 ABK19854 ABK19855 ABK19856 ABK19857 ABK19858 ABK19859 ABK19860 ABK19861 ABK19863 ABK19864 ABK19866 ABK19868 ABK19869 ABK19870 ABK19871 ABK19872 ABK19873 ABK19874 ABK19875 ABK19876 ABK19879 ABK19880 ABK96942 ABK96943 ABK96945 ABK96946 ABK96947 ABK96948 ABK96949 ABK96950 ABK96951 ABK96952 ABK96953 ABK96954 ABK96955 ABK96956 ABK96958 ABK96959 ABK96960 ABK96961 ABK96962 ABK96963 ABK96964 ABK96965 ABK96966 CAB75344 CAD29839 CAD29841 CAD29844 CAI41662 | ||||
| RNA Seq Atlas | 64663 | ||||