Version 5.4
Homo sapiens Gene: MTMR1
Summary
InnateDB Gene IDBG-88764.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTMR1
Gene Name myotubularin related protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000063601
Encoded Proteins
IDBP-88768
myotubularin related protein 1
IDBP-382328
myotubularin related protein 1
IDBP-382329
myotubularin related protein 1
IDBP-382331
myotubularin related protein 1
IDBP-382332
myotubularin related protein 1
IDBP-382333
myotubularin related protein 1
IDBP-382336
myotubularin related protein 1
IDBP-594147
myotubularin related protein 1
IDBP-592830
myotubularin related protein 1
IDBP-596967
myotubularin related protein 1
IDBP-589962
myotubularin related protein 1
IDBP-589331
myotubularin related protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:150692971-150765103
Strand Forward strand
Band q28
Transcripts
ENST00000370390 ENSP00000359417
ENST00000370387
ENST00000438018 ENSP00000389884
ENST00000436701 ENSP00000414925
ENST00000429965 ENSP00000390736
ENST00000434699 ENSP00000405946
ENST00000439546 ENSP00000404599
ENST00000445323 ENSP00000414178
ENST00000485376 ENSP00000434105
ENST00000488357 ENSP00000434514
ENST00000490316 ENSP00000436957
ENST00000493480
ENST00000493995 ENSP00000431992
ENST00000542156 ENSP00000445281
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004438 phosphatidylinositol-3-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015214
View Gene Order
ENSBTAG00000009657
Not yet available
Pathways
NETPATH
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
INOH website
Nicotinate Nicotinamide metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.347187 Hs.694993
RefSeq NM_003828 XM_005274766 XM_005274768 XM_006724854 XM_006724855 XM_006724856
HUGO
OMIM
CCDS CCDS14695
HPRD 02163
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca