Version 5.4
| Homo sapiens Gene: MAGEA10 | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-89076.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | MAGEA10 | ||||||||||||||||||
| Gene Name | melanoma antigen family A, 10 | ||||||||||||||||||
| Synonyms | CT1.10; MAGE10 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000124260 | ||||||||||||||||||
| Encoded Proteins |
melanoma antigen family A, 10
melanoma antigen family A, 10
melanoma antigen family A, 10
melanoma antigen family A, 10
|
||||||||||||||||||
| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011] This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80%% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011] |
||||||||||||||||||
| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome X:152133310-152138578 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q28 | ||||||||||||||||||
| Transcripts |
|
||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
| Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
| Biological Process |
|
||||||||||||||||||
| Cellular Component |
|
||||||||||||||||||
| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | C9J9A2 J3KT71 J3QRD7 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 4109 | ||||||||||||||||||
| UniGene | Hs.18048 | ||||||||||||||||||
| RefSeq | NM_001011543 NM_001251828 NM_021048 | ||||||||||||||||||
| HUGO | HGNC:6797 | ||||||||||||||||||
| OMIM | 300343 | ||||||||||||||||||
| CCDS | CCDS14705 | ||||||||||||||||||
| HPRD | 02280 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC116666 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 4109 | ||||||||||||||||||