Version 5.4
Homo sapiens Gene: PRAMEF1
Summary
InnateDB Gene IDBG-90267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRAMEF1
Gene Name PRAME family member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116721
Encoded Proteins
IDBP-90269
PRAME family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the PRAME (preferentially expressed antigen of melanoma) gene family which is expressed in many cancers but may function in reproductive tissues during development. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:12791397-12796628
Strand Forward strand
Band p36.21
Transcripts
ENST00000332296 ENSP00000332134
ENST00000400814
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042974 retinoic acid receptor binding
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0043066 negative regulation of apoptotic process
GO:0045596 negative regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.454859 Hs.531416
RefSeq NM_001024661 NM_001291380 NM_023013
HUGO
OMIM
CCDS CCDS148
HPRD 11272
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca