Version 5.4
Homo sapiens Gene: HMGCLL1
Summary
InnateDB Gene IDBG-91174.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMGCLL1
Gene Name 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146151
Encoded Proteins
IDBP-91176
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-91178
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-91180
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-91184
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-232521
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-381904
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-473405
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
IDBP-476756
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:55434369-55579214
Strand Reverse strand
Band p12.1
Transcripts
ENST00000370852 ENSP00000359889
ENST00000370850 ENSP00000359887
ENST00000274901 ENSP00000274901
ENST00000308161 ENSP00000309737
ENST00000398661 ENSP00000381654
ENST00000428842 ENSP00000412924
ENST00000508459 ENSP00000424309
ENST00000507223
ENST00000515546 ENSP00000426054
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004419 hydroxymethylglutaryl-CoA lyase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
GO:0046951 ketone body biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0016020 membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000007908
View Gene Order
ENSBTAG00000025718
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.147054 Hs.662317
RefSeq NM_001042406 NM_001287741 NM_001287746 NM_001287753 NM_019036
HUGO
OMIM
CCDS CCDS43474 CCDS43475 CCDS75472 CCDS75473
HPRD 13663
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca