Version 5.4
| Homo sapiens Gene: PAEP | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-92053.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | PAEP | ||||||||||||||||||
| Gene Name | progestagen-associated endometrial protein | ||||||||||||||||||
| Synonyms | GD; GdA; GdF; GdS; PAEG; PEP; PP14 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000122133 | ||||||||||||||||||
| Encoded Proteins |
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
progestagen-associated endometrial protein
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 9:135561756-135566955 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q34.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | P09466 | ||||||||||||||||||
| TrEMBL | A0A024R8D8 Q5T6T6 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 5047 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001018049 NM_002571 | ||||||||||||||||||
| HUGO | HGNC:8573 | ||||||||||||||||||
| OMIM | 173310 | ||||||||||||||||||
| CCDS | CCDS35173 | ||||||||||||||||||
| HPRD | 01411 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AL050169 AL354761 BC069451 BC069562 BC112304 BC113728 CH471090 J04129 M34046 M61886 | ||||||||||||||||||
| GenPept | AAA35801 AAA35802 AAA60147 AAA60148 AAH69451 AAH69562 AAI12305 AAI13729 CAB43305 CAI17197 EAW88166 EAW88167 EAW88168 | ||||||||||||||||||
| RNA Seq Atlas | 5047 | ||||||||||||||||||