Version 5.4
Homo sapiens Gene: TADA2B
Summary
InnateDB Gene IDBG-9216.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TADA2B
Gene Name transcriptional adaptor 2B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173011
Encoded Proteins
IDBP-9218
transcriptional adaptor 2B
IDBP-485040
transcriptional adaptor 2B
IDBP-484600
transcriptional adaptor 2B
IDBP-482755
transcriptional adaptor 2B
IDBP-484820
transcriptional adaptor 2B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al., 2003 [PubMed 12972612]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:7041899-7057952
Strand Forward strand
Band p16.1
Transcripts
ENST00000310074 ENSP00000308022
ENST00000506692 ENSP00000422398
ENST00000512388 ENSP00000423947
ENST00000515646 ENSP00000423181
ENST00000510704 ENSP00000425731
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0030914 STAGA complex
GO:0070461 SAGA-type complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029196
View Gene Order
ENSBTAG00000045569
Not yet available
Pathways
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.518614 Hs.625590
RefSeq NM_152293
HUGO
OMIM
CCDS CCDS47007
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca