Version 5.4
Homo sapiens Gene: NME3
Summary
InnateDB Gene IDBG-9255.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NME3
Gene Name NME/NM23 nucleoside diphosphate kinase 3
Synonyms c371H6.2; DR-nm23; NDPK-C; NDPKC; NM23-H3; NM23H3
Species Homo sapiens
Ensembl Gene ENSG00000103024
Encoded Proteins
IDBP-9257
non-metastatic cells 3, protein expressed in
IDBP-753197
IDBP-749844
IDBP-754165
IDBP-750322
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:1770286-1771730
Strand Reverse strand
Band p13.3
Transcripts
ENST00000219302 ENSP00000219302
ENST00000564252
ENST00000563854 ENSP00000454498
ENST00000563498 ENSP00000455435
ENST00000564628 ENSP00000456160
ENST00000566600
ENST00000567271
ENST00000561637
ENST00000565379
ENST00000568561 ENSP00000455271
ENST00000563367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0006915 apoptotic process
Cellular Component
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000073435
View Gene Order
ENSBTAG00000016552
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Folate metabolism pathway
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_002513 XM_005255332
HUGO
OMIM
CCDS CCDS10443
HPRD 03488
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca