Version 5.4
Homo sapiens Gene: AKIRIN2
Summary
InnateDB Gene IDBG-94215.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKIRIN2
Gene Name akirin 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135334
Encoded Proteins
IDBP-94217
akirin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:87675072-87702209
Strand Reverse strand
Band q15
Transcripts
ENST00000257787 ENSP00000257787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0009790 embryo development
GO:0010629 negative regulation of gene expression
GO:0010950 positive regulation of endopeptidase activity
GO:0032496 response to lipopolysaccharide
GO:0032755 positive regulation of interleukin-6 production
GO:0045087 innate immune response
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0017053 transcriptional repressor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028291
View Gene Order
ENSBTAG00000003764
Not yet available
Cross-References
SwissProt Q53H80
TrEMBL Q9NW35
UniProt Splice Variant
Entrez Gene 55122
UniGene Hs.485915
RefSeq NM_018064
HUGO HGNC:21407
OMIM 615165
CCDS CCDS5013
HPRD
IMGT
EMBL AK001204 AK222701 AL133211 BC000764 BC003042 BC005051
GenPept AAH00764 AAH03042 AAH05051 BAA91551 BAD96421 CAI21541
RNA Seq Atlas 55122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca