Version 5.4
Homo sapiens Gene: BACH2
Summary
InnateDB Gene IDBG-94358.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BACH2
Gene Name BTB and CNC homology 1, basic leucine zipper transcription factor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112182
Encoded Proteins
IDBP-94360
BTB and CNC homology 1, basic leucine zipper transcription factor 2
IDBP-94362
BTB and CNC homology 1, basic leucine zipper transcription factor 2
IDBP-293733
BTB and CNC homology 1, basic leucine zipper transcription factor 2
IDBP-385354
BTB and CNC homology 1, basic leucine zipper transcription factor 2
IDBP-600016
BTB and CNC homology 1, basic leucine zipper transcription factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:89926529-90296908
Strand Reverse strand
Band q15
Transcripts
ENST00000257749 ENSP00000257749
ENST00000343122 ENSP00000345642
ENST00000406998 ENSP00000384145
ENST00000453877 ENSP00000397668
ENST00000481150
ENST00000470301
ENST00000493201
ENST00000472023
ENST00000494747
ENST00000537989 ENSP00000437473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040270
View Gene Order
ENSBTAG00000020713
Not yet available
Cross-References
SwissProt
TrEMBL Q7Z6Q0
UniProt Splice Variant
Entrez Gene 60468
UniGene Hs.269764 Hs.595092 Hs.603052 Hs.614376
RefSeq NM_001170794 NM_021813 XM_005248758 XM_005248759
HUGO HGNC:14078
OMIM 605394
CCDS CCDS5026
HPRD 12012
IMGT
EMBL AL117342 AL121787 AL121941 AL158136 AL159164 AL353692
GenPept
RNA Seq Atlas 60468

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca