Homo sapiens Gene: CENPM
Summary
InnateDB Gene IDBG-9518.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPM
Gene Name centromere protein M
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100162
Encoded Proteins
centromere protein M
centromere protein M
centromere protein M
centromere protein M
centromere protein M
centromere protein M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:41938721-41947164
Strand Reverse strand
Band q13.2
Transcripts
ENST00000215980 ENSP00000215980
ENST00000396437
ENST00000402338 ENSP00000384731
ENST00000407253 ENSP00000384743
ENST00000404067 ENSP00000384814
ENST00000402420 ENSP00000384132
ENST00000472374 ENSP00000430624
ENST00000460824
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000278 mitotic cell cycle
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.208912
RefSeq NM_001002876 NM_001110215 NM_024053
HUGO
OMIM
CCDS CCDS14025 CCDS46719 CCDS46720
HPRD 12798
IMGT
EMBL
GenPept
RNA Seq Atlas