Version 5.4
Homo sapiens Gene: RCC1
Summary
InnateDB Gene IDBG-95231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCC1
Gene Name regulator of chromosome condensation 1
Synonyms CHC1; RCC1-I; SNHG3-RCC1
Species Homo sapiens
Ensembl Gene ENSG00000180198
Encoded Proteins
IDBP-95235
regulator of chromosome condensation 1
IDBP-95237
regulator of chromosome condensation 1
IDBP-95239
regulator of chromosome condensation 1
IDBP-231749
regulator of chromosome condensation 1
IDBP-377529
regulator of chromosome condensation 1
IDBP-377533
regulator of chromosome condensation 1
IDBP-377534
regulator of chromosome condensation 1
IDBP-377539
regulator of chromosome condensation 1
IDBP-377540
regulator of chromosome condensation 1
IDBP-722306
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:28505943-28539300
Strand Forward strand
Band p35.3
Transcripts
ENST00000373833 ENSP00000362939
ENST00000373832 ENSP00000362938
ENST00000373831 ENSP00000362937
ENST00000398958 ENSP00000381931
ENST00000427469 ENSP00000402740
ENST00000434290 ENSP00000405258
ENST00000419074 ENSP00000402260
ENST00000411533 ENSP00000413644
ENST00000430407 ENSP00000394650
ENST00000429051
ENST00000486790 ENSP00000472057
ENST00000478232
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 104 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 104 [view]
Protein-Protein 104 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005087 Ran guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0031492 nucleosomal DNA binding
GO:0042393 histone binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0007052 mitotic spindle organization
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0007088 regulation of mitosis
GO:0016032 viral process
GO:0032316 regulation of Ran GTPase activity
GO:0032853 positive regulation of Ran GTPase activity
GO:0051225 spindle assembly
Cellular Component
GO:0000790 nuclear chromatin
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028896
View Gene Order
ENSBTAG00000003788
Not yet available
Pathways
NETPATH
REACTOME
REACT_9395
Nuclear import of Rev protein pathway
REACT_6190
Rev-mediated nuclear export of HIV RNA pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_6288
Host Interactions of HIV factors pathway
REACT_6916
Interactions of Rev with host cellular proteins pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
myc_activpathway
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt
TrEMBL C9JMJ4 C9JQZ4 C9JRH2
UniProt Splice Variant
Entrez Gene 1104
UniGene Hs.469723
RefSeq NM_001048194 NM_001048195 NM_001048199 NM_001269
HUGO HGNC:1913
OMIM 179710
CCDS CCDS323 CCDS41295
HPRD 01559
IMGT
EMBL AL513497
GenPept
RNA Seq Atlas 1104

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca