Version 5.4
Homo sapiens Gene: TUBE1
Summary
InnateDB Gene IDBG-95530.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBE1
Gene Name tubulin, epsilon 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074935
Encoded Proteins
IDBP-95532
tubulin, epsilon 1
IDBP-812910
tubulin, epsilon 1
IDBP-812911
tubulin, epsilon 1
IDBP-812912
tubulin, epsilon 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:112070777-112087529
Strand Reverse strand
Band q21
Transcripts
ENST00000368662 ENSP00000357651
ENST00000368657
ENST00000441191
ENST00000604814
ENST00000605457 ENSP00000474458
ENST00000603651
ENST00000604743 ENSP00000475087
ENST00000604689
ENST00000604967 ENSP00000474989
ENST00000603621
ENST00000603722
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007098 centrosome cycle
GO:0051258 protein polymerization
GO:0051297 centrosome organization
Cellular Component
GO:0000242 pericentriolar material
GO:0005874 microtubule
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019845
View Gene Order
ENSBTAG00000013837
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_016262
HUGO
OMIM
CCDS CCDS5100
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca