Version 5.4
Homo sapiens Gene: RRAGC
Summary
InnateDB Gene IDBG-96571.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRAGC
Gene Name Ras-related GTP binding C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116954
Encoded Proteins
IDBP-96573
Ras-related GTP binding C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:38838198-38859823
Strand Reverse strand
Band p34.3
Transcripts
ENST00000373001 ENSP00000362092
ENST00000474456
ENST00000493015
ENST00000496778
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006184 GTP catabolic process
GO:0006351 transcription, DNA-templated
GO:0006915 apoptotic process
GO:0007264 small GTPase mediated signal transduction
GO:0008380 RNA splicing
GO:0016049 cell growth
GO:0034613 cellular protein localization
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028646
View Gene Order
ENSBTAG00000009368
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04150
mTOR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.532461 Hs.606534 Hs.621007 Hs.699784 Hs.732067
RefSeq NM_001271851 NM_022157
HUGO
OMIM
CCDS CCDS430
HPRD 12198
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca