Version 5.4
Homo sapiens Gene: GPR126
Summary
InnateDB Gene IDBG-97238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR126
Gene Name G protein-coupled receptor 126
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112414
Encoded Proteins
IDBP-97240
G protein-coupled receptor 126
IDBP-97242
G protein-coupled receptor 126
IDBP-97244
G protein-coupled receptor 126
IDBP-97246
G protein-coupled receptor 126
IDBP-600981
G protein-coupled receptor 126
IDBP-594666
G protein-coupled receptor 126
IDBP-589683
G protein-coupled receptor 126
IDBP-594485
G protein-coupled receptor 126
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:142301854-142446266
Strand Forward strand
Band q24.2
Transcripts
ENST00000296932 ENSP00000296932
ENST00000230173 ENSP00000230173
ENST00000367609 ENSP00000356581
ENST00000367608 ENSP00000356580
ENST00000415128
ENST00000435011 ENSP00000438366
ENST00000463637
ENST00000472054
ENST00000497898
ENST00000508295 ENSP00000444123
ENST00000541199 ENSP00000446287
ENST00000545477
ENST00000540208 ENSP00000439371
ENST00000538281
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039116
View Gene Order
ENSBTAG00000020707
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 57211
UniGene Hs.743302
RefSeq NM_001032394 NM_001032395 NM_020455 NM_198569 XM_005267061 XM_006715516 XM_006715517 XM_006715518
HUGO HGNC:13841
OMIM 612243
CCDS CCDS47489 CCDS47490 CCDS47491 CCDS55064
HPRD 17059
IMGT
EMBL
GenPept
RNA Seq Atlas 57211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca