Version 5.4
Homo sapiens Gene: FBXO30
Summary
InnateDB Gene IDBG-97566.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO30
Gene Name F-box protein 30
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000118496
Encoded Proteins
IDBP-97568
F-box protein 30
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:145793502-145814753
Strand Reverse strand
Band q24.3
Transcripts
ENST00000237281 ENSP00000237281
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047648
View Gene Order
ENSBTAG00000005376
Not yet available
Cross-References
SwissProt Q8TB52
TrEMBL
UniProt Splice Variant
Entrez Gene 84085
UniGene Hs.421095
RefSeq NM_032145 XM_005267159 XM_006715575
HUGO HGNC:15600
OMIM 609101
CCDS CCDS5208
HPRD 10953
IMGT
EMBL AF248640 AL356599 BC024326
GenPept AAH24326 AAK30299 CAI41119
RNA Seq Atlas 84085

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca