Version 5.4
Homo sapiens Gene: PLEKHG1
Summary
InnateDB Gene IDBG-97912.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHG1
Gene Name pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000120278
Encoded Proteins
IDBP-97914
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
IDBP-97916
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
IDBP-97918
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
IDBP-590738
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:150599863-150843665
Strand Forward strand
Band q25.1
Transcripts
ENST00000367328 ENSP00000356297
ENST00000367326 ENSP00000356295
ENST00000358517 ENSP00000351318
ENST00000475490 ENSP00000433107
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040624
View Gene Order
ENSBTAG00000009679
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.189781 Hs.734517
RefSeq NM_001029884 XM_005267064 XM_005267065 XM_005267066 XM_005267067 XM_006715521 XM_006715522
HUGO
OMIM
CCDS CCDS34552
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca