Version 5.4
Homo sapiens Gene: FAAH
Summary
InnateDB Gene IDBG-98116.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAAH
Gene Name fatty acid amide hydrolase
Synonyms FAAH-1; PSAB
Species Homo sapiens
Ensembl Gene ENSG00000117480
Encoded Proteins
IDBP-98118
fatty acid amide hydrolase
IDBP-806955
fatty acid amide hydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:46394265-46413848
Strand Forward strand
Band p33
Transcripts
ENST00000243167 ENSP00000243167
ENST00000468718
ENST00000493735
ENST00000484697 ENSP00000481641
ENST00000489366
ENST00000493636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor
GO:0017064 fatty acid amide hydrolase activity
GO:0047372 acylglycerol lipase activity
Biological Process
GO:0009062 fatty acid catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0031090 organelle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034171
View Gene Order
ENSBTAG00000007507
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.720143
RefSeq NM_001441
HUGO
OMIM
CCDS CCDS535
HPRD 04244
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca