Version 5.4
Homo sapiens Gene: ATPAF1
Summary
InnateDB Gene IDBG-98171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATPAF1
Gene Name ATP synthase mitochondrial F1 complex assembly factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000123472
Encoded Proteins
IDBP-98173
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-98175
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-592090
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-603726
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-587776
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-591520
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-593290
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-592248
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-592373
ATP synthase mitochondrial F1 complex assembly factor 1
IDBP-722554
IDBP-722433
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:46632737-46673867
Strand Reverse strand
Band p33
Transcripts
ENST00000371937 ENSP00000361005
ENST00000329231 ENSP00000330685
ENST00000492233 ENSP00000431258
ENST00000474020
ENST00000487193 ENSP00000433437
ENST00000460928
ENST00000526821 ENSP00000436690
ENST00000529214 ENSP00000436267
ENST00000534216 ENSP00000432771
ENST00000532925 ENSP00000435732
ENST00000525633
ENST00000542495 ENSP00000443588
ENST00000576409 ENSP00000460964
ENST00000574428 ENSP00000459167
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006461 protein complex assembly
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028710
View Gene Order
ENSBTAG00000000094
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.100874 Hs.597615 Hs.605920 Hs.628513
RefSeq NM_001042546 NM_001243728 NM_001256418 NM_022745
HUGO
OMIM
CCDS CCDS41327 CCDS541 CCDS57997 CCDS57998
HPRD 12332
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca