Version 5.4
Homo sapiens Gene: CYP4X1
Summary
InnateDB Gene IDBG-98222.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP4X1
Gene Name cytochrome P450, family 4, subfamily X, polypeptide 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186377
Encoded Proteins
IDBP-98224
cytochrome P450, family 4, subfamily X, polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:47023568-47050751
Strand Forward strand
Band p33
Transcripts
ENST00000371901 ENSP00000360968
ENST00000466294
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0070330 aromatase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047155
View Gene Order
ENSBTAG00000015647
Not yet available
Cross-References
SwissProt Q8N118
TrEMBL
UniProt Splice Variant
Entrez Gene 260293
UniGene Hs.439760
RefSeq NM_178033
HUGO HGNC:20244
OMIM 614999
CCDS CCDS544
HPRD 13110
IMGT
EMBL AK091806 AK098065 AK131355 AL450996 AL731892 AM040940 AY358537 BC028102 CH471059
GenPept AAH28102 AAQ88901 BAC03751 BAC05226 BAD18508 CAH71035 CAJ13826 EAX06882 EAX06883 EAX06884
RNA Seq Atlas 260293

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca