Version 5.4
Homo sapiens Gene: NPM2
Summary
InnateDB Gene IDBG-9959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPM2
Gene Name nucleophosmin/nucleoplasmin 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158806
Encoded Proteins
IDBP-9961
nucleophosmin/nucleoplasmin 2
IDBP-9963
nucleophosmin/nucleoplasmin 2
IDBP-234242
nucleophosmin/nucleoplasmin 2
IDBP-477582
nucleophosmin/nucleoplasmin 2
IDBP-482353
nucleophosmin/nucleoplasmin 2
IDBP-475848
nucleophosmin/nucleoplasmin 2
IDBP-483210
nucleophosmin/nucleoplasmin 2
IDBP-809635
nucleophosmin/nucleoplasmin 2
IDBP-809638
nucleophosmin/nucleoplasmin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:22024125-22036897
Strand Forward strand
Band p21.3
Transcripts
ENST00000289820 ENSP00000289820
ENST00000381530 ENSP00000370941
ENST00000397940 ENSP00000381032
ENST00000520125 ENSP00000429984
ENST00000521157 ENSP00000429413
ENST00000522813 ENSP00000428016
ENST00000518119 ENSP00000427741
ENST00000520180
ENST00000522953
ENST00000520456
ENST00000519373
ENST00000524322
ENST00000621538 ENSP00000481077
ENST00000615914 ENSP00000481018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003682 chromatin binding
GO:0019899 enzyme binding
GO:0042393 histone binding
Biological Process
GO:0006338 chromatin remodeling
GO:0007096 regulation of exit from mitosis
GO:0007338 single fertilization
GO:0009790 embryo development
GO:0009994 oocyte differentiation
GO:0043085 positive regulation of catalytic activity
GO:0045740 positive regulation of DNA replication
GO:0045836 positive regulation of meiosis
GO:0051054 positive regulation of DNA metabolic process
GO:0051260 protein homooligomerization
Cellular Component
GO:0000789 cytoplasmic chromatin
GO:0000790 nuclear chromatin
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047911
View Gene Order
ENSBTAG00000046918
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001286680 NM_001286681 NM_182795
HUGO
OMIM
CCDS CCDS6018 CCDS75703
HPRD 12160
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca