Version 5.4
Homo sapiens Gene: PLEKHG4B
Summary
InnateDB Gene IDBG-9991.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHG4B
Gene Name pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000153404
Encoded Proteins
IDBP-9993
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
IDBP-475997
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:140258-189970
Strand Forward strand
Band p15.33
Transcripts
ENST00000283426 ENSP00000283426
ENST00000502646 ENSP00000422493
ENST00000504041
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.535800
RefSeq NM_052909 XM_006714446
HUGO
OMIM
CCDS CCDS34124
HPRD 13900
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca