InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNHIT6

Summary

InnateDB Protein

IDBP-100061.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNHIT6

Protein Name

zinc finger, HIT-type containing 6

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000359606

InnateDB Gene

IDBG-100059 (ZNHIT6)

Protein Structure

UniProt Annotation

Function

Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis. {ECO:0000269PubMed:17636026}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000492	box C/D snoRNP assembly
GO:0042254	ribosome biogenesis

Cellular Component

GO:0070062	extracellular vesicular exosome
GO:0070761	pre-snoRNP complex

Protein Structure and Domains

PDB ID

InterPro

IPR007529 Zinc finger, HIT-type

PFAM

PF04438

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NWK9

PhosphoSite

PhosphoSite-Q9NWK9

TrEMBL

UniProt Splice Variant

Entrez Gene

54680

UniGene

Hs.707087

RefSeq

NP_060423

HUGO

HGNC:26089

OMIM

CCDS

CCDS707

HPRD

08630

IMGT

EMBL

AC092807 AC099561 AF308296 AK000736 AK000767 AK298149 AK314566 AL442074 BC026236 BC110898 BX323040 CH471097

GenPept

AAG48263 AAH26236 AAI10899 BAA91349 BAA91371 BAG37148 BAG60425 CAC09440 CAH73976 EAW73194 EAW73195