InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PKN2

Summary

InnateDB Protein

IDBP-100133.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PKN2

Protein Name

protein kinase N2

Synonyms

Pak-2; PAK2; PRK2; PRKCL2; PRO2042; STK7;

Species

Homo sapiens

Ensembl Protein

ENSP00000317851

InnateDB Gene

IDBG-100129 (PKN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.

Experimentally validated
Total	49 [view]
Protein-Protein	44 [view]
Protein-DNA	4 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016301	kinase activity

Biological Process

GO:0007165	signal transduction
GO:0016310	phosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005813	centrosome
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR011072 HR1 rho-binding repeat

PFAM

PF00168
PF02185

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00742

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B1AL79

UniProt Splice Variant

Entrez Gene

5586

UniGene

Hs.703016

RefSeq

HUGO

HGNC:9406

OMIM

602549

CCDS

HPRD

03972

IMGT

EMBL

AC119426 AL136381 CH471097

GenPept

EAW73162