Version 5.4
Homo sapiens Protein: GPR88
Summary
InnateDB Protein IDBP-100524.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR88
Protein Name G protein-coupled receptor 88
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000314223
InnateDB Gene IDBG-100522 (GPR88)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Expressed almost exclusively in striatum. {ECO:0000269PubMed:11056049}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007626 locomotory behavior
GO:0019228 neuronal action potential
GO:0050885 neuromuscular process controlling balance
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZN0
PhosphoSite PhosphoSite-Q9GZN0
TrEMBL
UniProt Splice Variant
Entrez Gene 54112
UniGene Hs.170053
RefSeq NP_071332
HUGO HGNC:4539
OMIM 607468
CCDS CCDS772
HPRD 16248
IMGT
EMBL AB042410 AB042411 AC099670 AY336999 BC036775
GenPept AAH36775 AAQ76787 BAB18247 BAB18248

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca