InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GSTM5

Summary

InnateDB Protein

IDBP-100903.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GSTM5

Protein Name

glutathione S-transferase mu 5

Synonyms

GSTM5-5; GTM5;

Species

Homo sapiens

Ensembl Protein

ENSP00000256593

InnateDB Gene

IDBG-100901 (GSTM5)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269PubMed:10587441}.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding

Biological Process

GO:0006749	glutathione metabolic process
GO:0006805	xenobiotic metabolic process
GO:0044281	small molecule metabolic process
GO:1901687	glutathione derivative biosynthetic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR003081 Glutathione S-transferase, Mu class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM