Version 5.4
Homo sapiens Protein: TSHB
Summary
InnateDB Protein IDBP-101337.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSHB
Protein Name thyroid stimulating hormone, beta
Synonyms TSH-B; TSH-BETA;
Species Homo sapiens
Ensembl Protein ENSP00000256592
InnateDB Gene IDBG-101335 (TSHB)
Protein Structure
UniProt Annotation
Function Indispensable for the control of thyroid structure and metabolism.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0009653 anatomical structure morphogenesis
GO:0016486 peptide hormone processing
GO:0033189 response to vitamin A
GO:0043627 response to estrogen
GO:0044267 cellular protein metabolic process
GO:0051592 response to calcium ion
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001545 Gonadotropin, beta subunit
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR029034 Cystine-knot cytokine
PFAM PF00007
PRINTS
PIRSF
SMART SM00068
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P01222
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 7252
UniGene
RefSeq NP_001264920
HUGO HGNC:12372
OMIM 188540
CCDS CCDS880
HPRD 11766
IMGT
EMBL AL109660 BC069298 M21024 M23670 M23671 M25164 S70587 X02866 X02867
GenPept AAA36782 AAA61235 AAB05845 AAB30828 AAH69298 CAA26618 CAA26619 CAI22270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca