Version 5.4
Homo sapiens Protein: SPAG17
Summary
InnateDB Protein IDBP-101477.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPAG17
Protein Name sperm associated antigen 17
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000337804
InnateDB Gene IDBG-101475 (SPAG17)
Protein Structure
UniProt Annotation
Function Seems to be important for the structural integrity of the central apparatus of the sperm axoneme. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250}. Note=Detected in the cytoplasm of round spermatids and in condensing spermatids. Localized to the central pair of the sperm flagellar axoneme. Colocalizes with SPAG6 on microtubules (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in testis. Expressed in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus. {ECO:0000269PubMed:15827353}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0036126 sperm flagellum
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6Q759
PhosphoSite PhosphoSite-Q6Q759
TrEMBL A7LBF9
UniProt Splice Variant
Entrez Gene 200162
UniGene Hs.598795
RefSeq NP_996879
HUGO HGNC:26620
OMIM
CCDS CCDS899
HPRD 10146
IMGT
EMBL AK091816 AL121993 AL137581 AL139345 AL513191 AY555274 EF989715
GenPept AAS66753 ABS28976 BAC03753 CAB70823 CAH71478 CAI22740 CAI22957

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca