Version 5.4
Homo sapiens Protein: GPR89A
Summary
InnateDB Protein IDBP-101788.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR89A
Protein Name G protein-coupled receptor 89A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000319673
InnateDB Gene IDBG-101784 (GPR89A)
Protein Structure
UniProt Annotation
Function Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:18794847}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005244 voltage-gated ion channel activity
GO:0008308 voltage-gated anion channel activity
Biological Process
GO:0006811 ion transport
GO:0007165 signal transduction
GO:0015031 protein transport
GO:0034765 regulation of ion transmembrane transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044070 regulation of anion transport
GO:0051452 intracellular pH reduction
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID
InterPro IPR022535 Golgi pH regulator, conserved domain
IPR025969 Abscisic acid G-protein coupled receptor-like domain
PFAM PF12537
PF12430
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B7ZAQ6
PhosphoSite PhosphoSite-B7ZAQ6
TrEMBL X5D7G6
UniProt Splice Variant
Entrez Gene 653519
UniGene Hs.645432
RefSeq NP_001091081
HUGO HGNC:31984
OMIM 612821
CCDS CCDS72857
HPRD
IMGT
EMBL AB097024 AB097025 AF132947 AF151035 AK021758 AK223223 AK301939 AK316371 AL133020 AL390725 AL445591 AY358966 BC003187 BC067816 BC146880 BT006679 BX511042 BX537254 CR628408 KJ534847 KJ534850 U78723
GenPept AAD27722 AAF21463 AAF36121 AAH03187 AAH67816 AAI46881 AAP35325 AAQ89325 AHW56487 AHW56490 BAC77377 BAC77378 BAD96943 BAG51045 BAG63359 BAH14742 CAH56393 CAH72386 CAI13224 CAI13712 CAI18821 CAM28366

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca