Version 5.4
Homo sapiens Protein: ANXA9
Summary
InnateDB Protein IDBP-102236.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANXA9
Protein Name annexin A9
Synonyms ANX31;
Species Homo sapiens
Ensembl Protein ENSP00000357943
InnateDB Gene IDBG-102234 (ANXA9)
Protein Structure
UniProt Annotation
Function Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. {ECO:0000269PubMed:10899159}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). {ECO:0000269PubMed:10899159}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0005544 calcium-dependent phospholipid binding
GO:0015464 acetylcholine receptor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0007268 synaptic transmission
GO:0016337 single organismal cell-cell adhesion
Cellular Component
GO:0005829 cytosol
GO:0009986 cell surface
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001464 Annexin
IPR009116 Annexin, type XXXI
IPR018502 Annexin repeat
PFAM PF00191
PRINTS PR00196
PR01812
PIRSF
SMART SM00335
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O76027
PhosphoSite PhosphoSite-O76027
TrEMBL
UniProt Splice Variant
Entrez Gene 8416
UniGene Hs.743315
RefSeq NP_003559
HUGO HGNC:547
OMIM 603319
CCDS CCDS975
HPRD
IMGT
EMBL AF230929 AJ009985 AL590133 BC005830 CR536481
GenPept AAG16780 AAH05830 CAA08933 CAG38720 CAI13335

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca