Version 5.4
Homo sapiens Protein: S100A5
Summary
InnateDB Protein IDBP-102692.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A5
Protein Name S100 calcium binding protein A5
Synonyms S100D;
Species Homo sapiens
Ensembl Protein ENSP00000357706
InnateDB Gene IDBG-102686 (S100A5)
Protein Structure
UniProt Annotation
Function Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites. {ECO:0000269PubMed:10882717}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
GO:0005509 calcium ion binding
GO:0008270 zinc ion binding
GO:0042803 protein homodimerization activity
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF00036
PF13202
PF13405
PF01023
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P33763
PhosphoSite PhosphoSite-P33763
TrEMBL Q52LE7
UniProt Splice Variant
Entrez Gene 6276
UniGene
RefSeq
HUGO HGNC:10495
OMIM 176991
CCDS CCDS1041
HPRD 01506
IMGT
EMBL BC093955 BC093957 BX470102 CH471121 Z18949 Z18950 Z18954
GenPept AAH93955 AAH93957 CAA79472 CAA79475 CAA79479 CAI14753 EAW53317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca