Version 5.4
Homo sapiens Protein: YY1AP1
Summary
InnateDB Protein IDBP-103298.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YY1AP1
Protein Name YY1 associated protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000355298
InnateDB Gene IDBG-103276 (YY1AP1)
Protein Structure
UniProt Annotation
Function Enhances transcription activation by YY1. May play a role in cell cycle regulation. {ECO:0000269PubMed:14744866, ECO:0000269PubMed:17541814}.
Subcellular Localization Cytoplasm. Nucleus.
Disease Associations
Tissue Specificity Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas. {ECO:0000269PubMed:11710830, ECO:0000269PubMed:12118372, ECO:0000269PubMed:14744866}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H869
PhosphoSite PhosphoSite-Q9H869
TrEMBL A3KFK1
UniProt Splice Variant
Entrez Gene 55249
UniGene Hs.584927
RefSeq NP_620832
HUGO HGNC:30935
OMIM 607860
CCDS
HPRD 08485
IMGT
EMBL AF203474 AF206328 AF466401 AK001737 AK023976 AK297562 AK303386 AL162734 AY604179 BC001655 BC001843 BC003500 BC008766 BC009358 BC014906 BC025272 BX088689 CH471121
GenPept AAH01655 AAH01843 AAH08766 AAH09358 AAH14906 AAL74055 AAL75971 AAO13249 AAT34990 BAA91871 BAB14748 BAG59954 BAG64442 CAH71642 CAH71643 CAH71644 CAH71646 CAH73350 CAH73351 CAH73352 CAH73354 CAQ07661 CAQ09422 EAW53052 EAW53055 EAW53056 EAW53057 EAW53060

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca