Version 5.4
Homo sapiens Protein: FCRL6
Summary
InnateDB Protein IDBP-103935.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRL6
Protein Name Fc receptor-like 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000357086
InnateDB Gene IDBG-103929 (FCRL6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed by cytolytic cells including NK cells, effector and effector-memory CD8+ T-cells. Expression among T-cells is greatly expanded in HIV-1 infected individuals, and includes not only effector and effector-memory CD8+ T-cells but also populations of CD4+ T-cells. {ECO:0000269PubMed:17213291}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019903 protein phosphatase binding
Biological Process
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6DN72
PhosphoSite PhosphoSite-Q6DN72
TrEMBL
UniProt Splice Variant
Entrez Gene 343413
UniGene Hs.196955
RefSeq NP_001004310
HUGO HGNC:31910
OMIM 613562
CCDS CCDS30912
HPRD 14177
IMGT
EMBL AK131201 AL590560 AY212514 AY513661 AY654627 AY654628
GenPept AAP47270 AAS82876 AAT66024 AAT66025 BAD18394 CAM14070 CAM14071 CAM14072

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca