InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PEA15

Summary

InnateDB Protein

IDBP-104014.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PEA15

Protein Name

phosphoprotein enriched in astrocytes 15

Synonyms

HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED;

Species

Homo sapiens

Ensembl Protein

ENSP00000357055

InnateDB Gene

IDBG-104008 (PEA15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	26 [view]
Protein-Protein	26 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006915	apoptotic process
GO:0008643	carbohydrate transport
GO:0042981	regulation of apoptotic process
GO:0043278	response to morphine
GO:0046325	negative regulation of glucose import
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Cellular Component

GO:0005737	cytoplasm
GO:0005875	microtubule associated complex

Protein Structure and Domains

PDB ID

InterPro

IPR001875 Death effector domain
IPR011029 Death-like domain

PFAM

PF01335

PRINTS

PIRSF

SMART

SM00031

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF153273 AF153274 AK095879 AK311762 AL121987 AL139011 BC002426 BC022554 BT007252 CH471121 X86809 Y13736

GenPept

AAD56775 AAH02426 AAH22554 AAP35916 BAG34705 BAG53155 CAA60499 CAA74076 EAW52733 EAW52734 EAW52735

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca