InnateDB Protein
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IDBP-104149.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TSTD1
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Protein Name
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thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000325518
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InnateDB Gene
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IDBG-226903 (TSTD1)
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Protein Structure
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Function |
Possible role in tumorigenesis.
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Subcellular Localization |
Cytoplasm, perinuclear region {ECO:0000269PubMed:12817473}. Note=Localized around the nuclear membranes.
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Disease Associations |
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Tissue Specificity |
Highly expressed in kidney, liver and skeletal muscle. Lower levels of expression in heart, colon, thymus, spleen, placenta and lung. Weakly expressed in brain, small intestine and peripheral blood leukocytes. Expressed at high levels in the breast carcinoma cell lines MCF-7 and MDA-MB-468 and at a lower level in the breast carcinoma cell line MDA-MB-231, the colon carcinoma call line LoVo and the lung carcinoma cell line A- 549. No expression in the cell lines EFO-27 and HeLa, or the normal breast tissue cell lines MCF-10A and H184A1. Detected in invasive ductal carcinoma, but not in the adjacent tissues. {ECO:0000269PubMed:12817473}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001763
Rhodanese-like domain
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PFAM |
PF00581
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PRINTS |
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PIRSF |
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SMART |
SM00450
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NFU3
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PhosphoSite |
PhosphoSite-Q8NFU3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
100131187
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UniGene |
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RefSeq |
NP_001106676
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HUGO |
HGNC:35410
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OMIM |
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CCDS |
CCDS44258
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HPRD |
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IMGT |
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EMBL |
AF439442
AL591806
BC001699
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GenPept |
AAH01699
AAM69839
AAM69840
CAI15367
CAI15368
CAI15369
CAI15370
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