Version 5.4
Homo sapiens Protein: UFC1
Summary
InnateDB Protein IDBP-104195.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UFC1
Protein Name ubiquitin-fold modifier conjugating enzyme 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356982
InnateDB Gene IDBG-104193 (UFC1)
Protein Structure
UniProt Annotation
Function E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. {ECO:0000269PubMed:15071506}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0071568 UFM1 conjugating enzyme activity
Biological Process
GO:0034976 response to endoplasmic reticulum stress
GO:0071569 protein ufmylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR014806 Ubiquitin-fold modifier-conjugating enzyme 1
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF08694
PRINTS
PIRSF PIRSF008716
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y3C8
PhosphoSite PhosphoSite-Q9Y3C8
TrEMBL
UniProt Splice Variant
Entrez Gene 51506
UniGene Hs.301412
RefSeq NP_057490
HUGO HGNC:26941
OMIM 610554
CCDS CCDS1220
HPRD 15643
IMGT
EMBL AB154405 AF151884 AF161504 AK292776 AL590714 BC005187 CH471121
GenPept AAD34121 AAF29119 AAH05187 BAD15374 BAF85465 CAH72141 EAW52646 EAW52647

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca