InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MGST3

Summary

InnateDB Protein

IDBP-104477.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MGST3

Protein Name

microsomal glutathione S-transferase 3

Synonyms

GST-III;

Species

Homo sapiens

Ensembl Protein

ENSP00000356860

InnateDB Gene

IDBG-104471 (MGST3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	9 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0004601	peroxidase activity
GO:0004602	glutathione peroxidase activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006805	xenobiotic metabolic process
GO:0007165	signal transduction
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process
GO:1901687	glutathione derivative biosynthetic process

Cellular Component

GO:0005635	nuclear envelope
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein

PFAM

PF01124

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF026977 AK312103 AL356441 AL451074 AY388493 BC000505 BC003034 BC005964 CH471067 CR450359 DQ185045

GenPept

AAB82609 AAH00505 AAH03034 AAH05964 AAQ81301 ABD14425 BAG35039 CAG29355 CAH74057 EAW90752 EAW90753 EAW90756

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca