Version 5.4
Homo sapiens Protein: SLC30A4
Summary
InnateDB Protein IDBP-10463.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC30A4
Protein Name solute carrier family 30 (zinc transporter), member 4
Synonyms ZNT4;
Species Homo sapiens
Ensembl Protein ENSP00000261867
InnateDB Gene IDBG-10461 (SLC30A4)
Protein Structure
UniProt Annotation
Function Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
Subcellular Localization Endosome membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0009636 response to toxic substance
GO:0055069 zinc ion homeostasis
GO:0055085 transmembrane transport
GO:0061088 regulation of sequestering of zinc ion
GO:0071577 zinc ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002524 Cation efflux protein
PFAM PF01545
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14863
PhosphoSite PhosphoSite-O14863
TrEMBL
UniProt Splice Variant
Entrez Gene 7782
UniGene Hs.635817
RefSeq NP_037441
HUGO HGNC:11015
OMIM 602095
CCDS CCDS10125
HPRD 03651
IMGT
EMBL AF025409 AK290874 BC026089 CH471082
GenPept AAB82561 AAH26089 BAF83563 EAW77316

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca