InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NME7

Summary

InnateDB Protein

IDBP-104648.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NME7

Protein Name

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000356785

InnateDB Gene

IDBG-104646 (NME7)

Protein Structure

UniProt Annotation

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	20 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004550	nucleoside diphosphate kinase activity
GO:0005524	ATP binding
GO:0046872	metal ion binding

Biological Process

GO:0003351	epithelial cilium movement
GO:0006165	nucleoside diphosphate phosphorylation
GO:0006183	GTP biosynthetic process
GO:0006228	UTP biosynthetic process
GO:0006241	CTP biosynthetic process
GO:0007368	determination of left/right symmetry
GO:0007420	brain development
GO:0042073	intraciliary transport
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway
GO:0060972	left/right pattern formation