InnateDB Protein
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IDBP-104653.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BLZF1
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Protein Name
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basic leucine zipper nuclear factor 1
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Synonyms
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GOLGIN-45; JEM-1; JEM-1s; JEM1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000356782
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InnateDB Gene
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IDBG-104649 (BLZF1)
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Protein Structure
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Function |
Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.
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Subcellular Localization |
Golgi apparatus lumen {ECO:0000269PubMed:11056056, ECO:0000269PubMed:11739401, ECO:0000269PubMed:9129147}.Isoform 1: Nucleus.Isoform 2: Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Also found in cell lines derived from several hematopoietic pathologies, such as T-cell leukemia, pro-B, pre-B, myeloma, and plasmacytoma cell lines, but not in Burkitt lymphoma cells. {ECO:0000269PubMed:11056056, ECO:0000269PubMed:11739401, ECO:0000269PubMed:9129147}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
23
[view]
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Protein-Protein |
19
[view]
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Protein-DNA |
4
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR013183
DASH complex subunit Hsk3 like
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PFAM |
PF08227
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H2G9
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PhosphoSite |
PhosphoSite-Q9H2G9
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TrEMBL |
Q5T534
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UniProt Splice Variant |
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Entrez Gene |
8548
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UniGene |
Hs.626787
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RefSeq |
XP_005245618
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HUGO |
HGNC:1065
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OMIM |
608692
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CCDS |
CCDS1278
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HPRD |
16367
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IMGT |
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EMBL |
AF272386
AF272387
AF272388
AF273875
AF288161
AF288162
AL021068
AL356852
BC020716
CH471067
U79751
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GenPept |
AAB63110
AAG37821
AAG37822
AAG37835
AAH20716
CAI19240
CAI19242
EAW90837
EAW90838
EAW90839
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