InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TNN

Summary

InnateDB Protein

IDBP-104973.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNN

Protein Name

tenascin N

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000239462

InnateDB Gene

IDBG-104971 (TNN)

Protein Structure

UniProt Annotation

Function

Involved in neurite outgrowth and cell migration in hippocampal explants. {ECO:0000250UniProtKB:Q80Z71}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0007160	cell-matrix adhesion
GO:0007409	axonogenesis
GO:0016049	cell growth
GO:0016477	cell migration

Cellular Component

GO:0005575	cellular_component
GO:0005578	proteinaceous extracellular matrix
GO:0009986	cell surface

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR003961 Fibronectin, type III
IPR013111 EGF-like domain, extracellular

PFAM

PF00008
PF00147
PF00041
PF01108
PF07974

PRINTS

PIRSF

SMART

SM00181
SM00186
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UQP3

PhosphoSite

PhosphoSite-Q9UQP3

TrEMBL

UniProt Splice Variant

Entrez Gene

63923

UniGene

Hs.629935

RefSeq

NP_071376

HUGO

HGNC:22942

OMIM

CCDS

CCDS30943

HPRD

IMGT

EMBL

AL049689 BC136619 Z99297 Z99715

GenPept

AAI36620 CAB41260 CAI19286 CAI19966