InnateDB Protein
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IDBP-105182.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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XPR1
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Protein Name
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xenotropic and polytropic retrovirus receptor 1
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Synonyms
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SYG1; X3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000356561
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InnateDB Gene
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IDBG-105178 (XPR1)
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Protein Structure
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Function |
May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses. {ECO:0000250, ECO:0000269PubMed:9988277, ECO:0000269PubMed:9990033}.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle. {ECO:0000269PubMed:9927670, ECO:0000269PubMed:9990033}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0007186
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G-protein coupled receptor signaling pathway
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Cellular Component |
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PDB ID |
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InterPro |
IPR004331
SPX, N-terminal
IPR004342
EXS, C-terminal
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PFAM |
PF03105
PF03124
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UBH6
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PhosphoSite |
PhosphoSite-Q9UBH6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9213
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UniGene |
Hs.623603
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RefSeq |
NP_001129141
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HUGO |
HGNC:12827
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OMIM |
605237
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CCDS |
CCDS44284
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HPRD |
05574
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IMGT |
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EMBL |
AF089744
AF099082
AF115389
AL133058
AL137583
AL162431
AL358434
AL590085
BC041142
CH471067
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GenPept |
AAD08928
AAD10196
AAD17211
AAH41142
CAB61383
CAB70825
CAH70457
CAH70458
CAH74089
CAH74090
CAH74113
CAH74114
EAW91086
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