InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STX6

Summary

InnateDB Protein

IDBP-105192.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STX6

Protein Name

syntaxin 6

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000258301

InnateDB Gene

IDBG-105188 (STX6)

Protein Structure

UniProt Annotation

Function

Involved in intracellular vesicle trafficking.

Subcellular Localization

Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding

Biological Process

GO:0006886	intracellular protein transport
GO:0006906	vesicle fusion
GO:0007032	endosome organization
GO:0016192	vesicle-mediated transport
GO:0042147	retrograde transport, endosome to Golgi
GO:0048193	Golgi vesicle transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005769	early endosome
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030136	clathrin-coated vesicle
GO:0031201	SNARE complex
GO:0032588	trans-Golgi network membrane
GO:0048471	perinuclear region of cytoplasm