InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RABIF

Summary

InnateDB Protein

IDBP-105883.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RABIF

Protein Name

RAB interacting factor

Synonyms

MSS4; RASGFR3; RASGRF3;

Species

Homo sapiens

Ensembl Protein

ENSP00000356231

InnateDB Gene

IDBG-105881 (RABIF)

Protein Structure

UniProt Annotation

Function

Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	15 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0043547	positive regulation of GTPase activity
GO:0061025	membrane fusion