Version 5.4
Homo sapiens Protein: SOX13
Summary
InnateDB Protein IDBP-106006.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX13
Protein Name SRY (sex determining region Y)-box 13
Synonyms ICA12; Sox-13;
Species Homo sapiens
Ensembl Protein ENSP00000356172
InnateDB Gene IDBG-106002 (SOX13)
Protein Structure
UniProt Annotation
Function Binds to the sequence 5'-AACAAT-3'. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}.
Disease Associations
Tissue Specificity Highly expressed in kidney, lung, and liver and low expression in thymus, brain, spleen, and muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0045586 regulation of gamma-delta T cell differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UN79
PhosphoSite PhosphoSite-Q9UN79
TrEMBL E9PPW0
UniProt Splice Variant
Entrez Gene 9580
UniGene Hs.201671
RefSeq NP_005677
HUGO HGNC:11192
OMIM 604748
CCDS CCDS44299
HPRD
IMGT
EMBL AF083105 AF098915 AF116571 AF149301 AK304192 AK304801 AL592146 BC106038 CH471067
GenPept AAC83687 AAD16237 AAD50120 AAF23875 AAI06039 BAG65072 BAG65551 CAI16596 EAW91500

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca