Version 5.4
Homo sapiens Protein: AVPR1B
Summary
InnateDB Protein IDBP-106208.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AVPR1B
Protein Name arginine vasopressin receptor 1B
Synonyms AVPR3;
Species Homo sapiens
Ensembl Protein ENSP00000356094
InnateDB Gene IDBG-106206 (AVPR1B)
Protein Structure
UniProt Annotation
Function Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005000 vasopressin receptor activity
GO:0005080 protein kinase C binding
Biological Process
GO:0001992 regulation of systemic arterial blood pressure by vasopressin
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000628 Vasopressin V1B receptor
IPR001224 Vasopressin V1A receptor
IPR001817 Vasopressin receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
PFAM PF00001
PF10320
PF10323
PRINTS PR00237
PR00897
PR00752
PR00896
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47901
PhosphoSite PhosphoSite-P47901
TrEMBL
UniProt Splice Variant
Entrez Gene 553
UniGene Hs.1372
RefSeq NP_000698
HUGO HGNC:896
OMIM 600264
CCDS CCDS73015
HPRD 02600
IMGT
EMBL AF030512 AF101726 AF152238 BX571818 D31833 DQ194816 EU432111 L37112
GenPept AAA65687 AAB84293 AAD17892 AAF33681 ABA03171 ABY87910 BAA06621 CAH73262

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca